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Home Dermal Fillers SYNVISC ONE solution injectable (1x6ml)
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SYNVISC ONE solution injectable (1x6ml)

$215.00

Hylan GF 20 is biologically similar to hyaluronan . Hyaluronan is a component of synovial fluid which provides its viscoelasticity . However, the mechanical properties ( viscoelastic ) of Hylan GF 20 are greater than those of synovial fluid and hyaluronan solutions similar concentration . Hylan GF 20 has an elasticity ( storage modulus G ‘) at 2.5 Hz 111 Pascals (Pa) ± 13 and a viscosity ( loss coefficient G ”) of 25 ± 2 Pa . The elasticity and viscosity of the synovial fluid of the knee of subjects aged 18-27 years measured with a comparable method is 2.5 Hz G = 117 ± 13 Pa , 45 Pa G ” = ± 8. Hylans are metabolized in the body in the same way that hyaluronan and their degradation products are not toxic .

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Description

 

F Hylan G- 20 is available in two forms :

Synvisc , 2 ml: glass syringe of 2.25 ml ( boxes 1 [ 3401078489921 ACL ] and 3 [ 3401076479283 ACL ] ) .

Synvisc -One , 6 ml: glass syringe 10 ml (ACL 3401048640222 ) .

Hylan GF 20 is a viscoelastic fluid , sterile and non-pyrogenic containing hylan . Hylans are derivatives of hyaluronan ( sodium hyaluronate ) , and they are composed of repeating disaccharide units of N- acetylglucosamine and sodium glucuronate .

The hylan A has an average molecular weight of 6 million daltons and hylan B gel is a hydrated . Hylan GF 20 contains hylan A and hylan B ( 8.0 mg ± 2.0 mg / ml ) solution in physiological buffered saline ( pH 7.2 ± 0.3 ) .

composition

To 1 mL ( 20 Hylan GF ) : hylan 8.0 mg , 8.5 mg sodium chloride , 0.16 mg disodium phosphate , sodium dihydrogen phosphate hydrate 0.04 mg Water for injection qs .

Synvisc contains 2 ml of Hylan G- F 20. Synvisc -One contains 6 ml of Hylan G- F 20.

properties

Hylan GF 20 is biologically similar to hyaluronan . Hyaluronan is a component of synovial fluid which provides its viscoelasticity . However, the mechanical properties ( viscoelastic ) of Hylan GF 20 are greater than those of synovial fluid and hyaluronan solutions similar concentration . Hylan GF 20 has an elasticity ( storage modulus G ‘) at 2.5 Hz 111 Pascals (Pa) ± 13 and a viscosity ( loss coefficient G ”) of 25 ± 2 Pa . The elasticity and viscosity of the synovial fluid of the knee of subjects aged 18-27 years measured with a comparable method is 2.5 Hz G = 117 ± 13 Pa , 45 Pa G ” = ± 8. Hylans are metabolized in the body in the same way that hyaluronan and their degradation products are not toxic .

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